Dr. Amit Mathai Fenn

Computational Biologist | Postdoctoral Researcher at TUM & Helmholtz Munich

Advancing plant-microbe genomics and alternative splicing research through computational innovation and multi-omics integration

About

I am a computational biologist specializing in alternative splicing, plant-microbe genomics, and transcriptomics. Currently, I serve as a Postdoctoral Researcher at the Technical University of Munich (TUM) Weihenstephan and Helmholtz Munich, investigating molecular diversity in plant-microbe interactions through comparative genomics as part of the TRR 356 collaborative research initiative.

I earned my PhD in Bioinformatics from TUM (2019-2022), where my dissertation "Towards Reproducibility in Alternative Splicing Analysis" focused on developing reproducible methodologies for analyzing splice variants, with applications to dilated cardiomyopathy.

My research combines computational innovation with biological insights to address fundamental questions in genomics and systems biology, bridging tool development and applied research.

Research Interests

DICAST - Alternative Splicing Benchmark

Lead Developer

Automated pipeline for detecting and analyzing alternative splicing events. Benchmarking framework for RNA-Seq analysis tools with reproducible methodologies for splice variant characterization.

RNA-Seq Bioinformatics Open Source
View documentation →

Environmental Microbiome Analysis

Collaborator

Analyzing nanopore metagenomics data for environmental monitoring. Computational approaches for characterizing microbial communities in complex samples.

Metagenomics Nanopore Environmental Science
View preprint →

Oat Genome Assembly and Analysis

Contributor

Comprehensive genomic analysis of cultivated oat (Avena sativa), including assembly, annotation, and comparative analysis to understand evolutionary relationships and functional features of this cereal crop.

Plant Genomics Genome Assembly Comparative Genomics
View publication →

Workshops & Short Courses

Introduction to nf-core Pipelines

Workshop Instructor

Hands-on workshop introducing nf-core bioinformatics pipelines, covering pipeline execution, configuration, and best practices for reproducible computational workflows.

Bioinformatics Nextflow Reproducibility
View materials →

Curriculum Vitae

Download my complete CV for detailed information about my education, experience, and publications.

Download CV (PDF)

Highlights

Current Positions

Postdoctoral Researcher Feb 2024-Present

Technical University of Munich (TUM) Weihenstephan

Kamal Research Group, Plant Genomes and Systems Biology

TRR 356 Plant Microbe Initiative - Z03

Postdoctoral Researcher 2023-2024

Helmholtz Munich Neuherberg

Helmholtz Pioneer Campus

Education

Ph.D. in Bioinformatics 2019-2022

Technical University of Munich (TUM)

Dissertation: "Towards Reproducibility in Alternative Splicing Analysis"

M.Sc. in Biology 2017-2019

Ludwig-Maximilians University (LMU) Munich

Specialization: Cell Biology & Biochemistry

Key Skills

Computational Biology
  • Alternative Splicing Analysis
  • RNA-Seq & Transcriptomics
  • Multi-Omics Integration
  • Network Biology
Technical Skills
  • Bioinformatics Tool Development
  • Nanopore Metagenomics
  • High-Performance Computing
  • Statistical Analysis
Research Areas
  • Plant Genomics
  • Plant-Microbe Interactions
  • Comparative Genomics
  • Systems Biology

Contact

I'm interested in discussing research collaborations, computational biology projects, and opportunities at the intersection of genomics and systems biology.

Academic Profile

Google Scholar

ORCID

Professional

LinkedIn

GitHub